Molecular Genetics

The Molecular Genetics Diagnostic Laboratory provides DNA and RNA-based molecular testing services for a wide variety of indications, including inherited genetic disorders, pharmacogenomic risk modification and molecular characterization of hematological and solid tumors. Molecular techniques are used for direct mutation analysis and for monitoring of disease status and progression. Once a mutation in an affected individual is identified, genetic testing for other family members is available, providing crucial information for the provision of genetic counseling and determination of recurrence risk.

Our molecular genetics board-certified laboratory directors and board certified genetic counselor are available for consultation to discuss test results, provide recommendations for diagnosis and management and to help arrange molecular genetic testing for disorders not tested for in this laboratory. Genetic counseling for pediatric, adult and pregnant patients is available within the Detroit Medical Center.

The increased demand for molecular genetic testing is accompanied by a responsibility to ensure that the technology is used appropriately. We support the responsible use of genetic testing by providing pre-and post-test support for referring clinicians. Test requests are monitored for “reason for referral” to ensure that we provide the most accurate interpretation. The medical laboratory director is also a board-certified clinical geneticist and is available to discuss the limitations of molecular genetic testing and recommend alternative testing strategies, when appropriate.