Aid in the determination of dosage for thiopurine drugs
Required Patient Information:
Personal and Family History of clinical symptoms and/or previous test results (if any)
Turn Around Time:
Specimen type: Whole blood
Allele specific TaqMan probe pairs will be used to assay for the TPMT allele variants TPMT*2 (c.238G>C), TPMT*3A ([c.460G>A;c.719A>G]), TPMT*3B (c.460G>A) and TPMT*3C (c.719A>G). These variants account for >95% of inherited TPMT enzyme deficiency.