BCR-ABL1 Kinase Domain Mutation Analysis

¨ BCR-ABL1 Kinase Domain Mutation Analysis

Order Code: 333682                       

CPT Codes:  81403, G0452

Indication : Tyrosine kinase inhibitor drug resistance

Required Patient Information: Clinical Diagnosis

Turn Around Time:  7-10 days

Specimen type: Whole Blood, Bone Marrow

Methodology: Testing for the acquired mutations in the ABL1 kinase domain will be performed by RT-PCR of the BCR-ABL1 translocation followed by nested PCR of the ABL1 kinase domain region and bidirectional sequencing to identify mutations associated with drug resistance.