Methylene Tetrahydrofolate Reductase

- Methylene Tetrahydrofolate Reductase (MTHFR)-related Thrombophilia/Methotrexate Toxicity

Order Code: 333401

CPT Codes: 81291, G0452

Indication:  Carrier Screening, Clinical Diagnosis

Required Patient Information: Personal and Family History of clinical symptoms and/or previous test results (if any).  Routine carrier screening in asymptomatic individuals under the age of 18 will require a signed consent form.

Turn Around Time:  7-14 days

Specimen type: Whole Blood

Methodology:  PCR based assays using the Invader chemistry are used to detect 677C>T and 1298A>C variants in MTHFR gene.